GE Healthcare 2009 Educational Services CD

Forum format 6 guest speakers each speaking on a different aspect of Infection Control/Prevention


MRSA BSI dramitc rise if MRSA esp in ICUs esp abcess and cellulitis
2000 NNIS stats shpow MRSA antibiotic resistance static rate
staph aureus MRSA rose from 37% -64% Most MRSA was non Beta lactam resistant

Community MRSA
non Beta lactam suseptible
novel chromosomal cassette SCCMEC Type IV
dermonecrotic crytotoxin PVL
strain USA 300
25% cause cellulitis and some bacteremias

Hospital MRSA
Resistant to non beta lactams
chromosomal cassett SCCMEC type II
infrequently encoded cytotoxin
multiple strains
predominate cause is bacteremias not cellulitis


MRSA
higher mortality
greater length of stay overall in hospital
increased costs for MRSA infection vs non MRSA infection $10,000 - $50,000 costs

where is MRSA found in patieents
colonized/respiratory tract 62%
soft tissue 18%
bone/joint 10%
catheter 1%
blood 11%
other 8%

MRSA is due to spread from a few clones
increasing incidence of MRSA suggests failure of infection prevention practices
Main goal is to prevent coloni will prevent infectionszation of non-colonized individuals